Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
YANG TAIYIN
  2. Issuer Name and Ticker or Trading Symbol
GILEAD SCIENCES INC [GILD]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
SVP, Pharm Dev & Mfg
(Last)
(First)
(Middle)
GILEAD SCIENCES, INC., 333 LAKESIDE DRIVE
3. Date of Earliest Transaction (Month/Day/Year)
02/13/2006
(Street)

FOSTER CITY, CA 94404
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 02/13/2006   M   12,000 A $ 2.8594 138,615 D  
Common Stock 02/13/2006   M   58,664 A $ 4.4688 197,279 D  
Common Stock 02/13/2006   M   2,000 A $ 7.0782 199,279 D  
Common Stock 02/13/2006   M   4,800 A $ 7.4063 204,079 D  
Common Stock 02/13/2006   M   3,000 A $ 9.3438 207,079 D  
Common Stock 02/13/2006   M   11,624 A $ 7.2969 218,703 D  
Common Stock 02/13/2006   M   1,888 A $ 11.7579 220,591 D  
Common Stock 02/13/2006   M   3,208 A $ 7.3985 223,799 D  
Common Stock 02/13/2006   M   1,000 A $ 9.81 224,799 D  
Common Stock 02/13/2006   M   862 A $ 16.4375 225,661 D  
Common Stock               3,992 I by Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Incentive Stock Option (right to buy) $ 2.8594 02/13/2006   M     12,000   (1) 07/22/2008 Common Stock 12,000 $ 0 0 D  
Incentive Stock Option (right to buy) $ 4.4688 02/13/2006   M     58,664   (2) 01/25/2009 Common Stock 58,664 $ 0 0 D  
Incentive Stock Option (right to buy) $ 7.0782 02/13/2006   M     2,000   (3) 01/26/2010 Common Stock 2,000 $ 0 0 D  
Incentive Stock Option (right to buy) $ 7.2969 02/13/2006   M     11,624   (4) 07/21/2009 Common Stock 11,624 $ 0 0 D  
Incentive Stock Option (right to buy) $ 7.3985 02/13/2006   M     3,208   (5) 01/17/2001 Common Stock 3,208 $ 0 0 D  
Incentive Stock Option (right to buy) $ 7.4063 02/13/2006   M     4,800   (6) 04/05/2010 Common Stock 4,800 $ 0 0 D  
Incentive Stock Option (right to buy) $ 9.3438 02/13/2006   M     3,000   (7) 07/20/2010 Common Stock 3,000 $ 0 0 D  
Incentive Stock Option (right to buy) $ 9.81 02/13/2006   M     1,000   (8) 04/17/2011 Common Stock 1,000 $ 0 1,000 D  
Incentive Stock Option (right to buy) $ 11.7579 02/13/2006   M     1,888   (9) 11/07/2010 Common Stock 1,888 $ 0 0 D  
Incentive Stock Option (right to buy) $ 16.4375 02/13/2006   M     862   (10) 01/29/2012 Common Stock 862 $ 0 6,586 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
YANG TAIYIN
GILEAD SCIENCES, INC.
333 LAKESIDE DRIVE
FOSTER CITY, CA 94404
      SVP, Pharm Dev & Mfg  

Signatures

 /s/ Taiyin Yang   02/15/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Options vested 20% on the July 23, 1999, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at July 23, 2003.
(2) Options vested 20% on the January 26, 2000, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at January 26, 2004.
(3) Options vested 20% on the January 26, 2001, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at January 26, 2005.
(4) Options vested 20% on the July 22, 2000, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at July 22, 2004.
(5) Options vested 20% on the January 18, 2002, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at January 18, 2006.
(6) Options vested 20% on the April 5, 2001, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at April 5, 2005.
(7) Options vested 20% on the July 20, 2001, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at July 20, 2005.
(8) Options vested 20% on the April 18, 2002, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at April 18, 2006.
(9) Options vested 20% on the November 8, 2001, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at November 8, 2005.
(10) Options vested 20% on the January 30, 2003, the first anniversary date of the grant. The balance vested every three months thereafter and was fully vested at January 30, 2007.

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