Ownership Submission
FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0362
Expires: January 31, 2005
Estimated average burden hours per response... 1.0

1. Name and Address of Reporting Person *
APPELBAUM MICHAEL
 2. Issuer Name and Ticker or Trading Symbol
MEDAREX INC [MEDX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)

MEDAREX, INC., 707 STATE ROAD		 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
12/31/2006
(Street)


PRINCETON, NJ 08540		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price
Common Stock 01/01/2006   G 845.66 D $ (1) 52,008.34 (6) I See footnote. (3)
Common Stock 01/01/2006   G 845.66 A $ (1) 845.66 I See footnote. (4)
Common Stock 01/01/2006   G 845.66 D $ (2) 51,162.68 (6) I See footnote. (3)
Common Stock 01/01/2006   G 845.66 A $ (2) 845.66 I See footnote. (5)
Common Stock             20,164 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
APPELBAUM MICHAEL
MEDAREX, INC.
707 STATE ROAD
PRINCETON, NJ 08540		   X      

Signatures

MICHAEL APPELBAUM 01/29/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Transfer of 845.56 shares of common stock from Appelbaum Family Investments LLP to the Appelbaum Children's Trust. The reporting person is a co-trustee of the Appelbaum Living Trust, which is the general partner and a limited partner of the Appelbaum Family Investments, LLP. The reporting person is a co-trustee of the Appelbaum Children's Trust.
(2) Transfer of 845.56 shares of common stock from Appelbaum Family Investments LLP to Appelbaum Grandchildren's Trust. The reporting person is a co-trustee of the Appelbaum Living Trust, which is the general partner of a limited partner of the Appelbaum Family Investments, LLP. The reporting person is a co-trustee of the Appelbaum Grandchildren's Trust.
(3) The shares are held by Appelbaum Family Investments LLP. The reporting person is a co-trustee of the Appelbaum Living Trust which is the general partner and a limited partner of the Appelbaum Family Investments, LLP.
(4) The shares are held by the Appelbaum Children's Trust. The reporting person is a co-trustee of the Appelbaum Children's Trust.
(5) The shares are held by the Appelbaum Grandchildren's Trust. The reporting person is a co-trustee of te Appelbaum Grandchildren's Trust.
(6) Includes separate gifts of limited partnership interests in the Appelbaum Family Investment LLP to the reporting person's two adult children residing outside the reporting person's household. Each gift represented a 0.5% interest in the Appelbaum Family Investments LLP.

Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.