The information contained in this preliminary prospectus supplement is subject to completion and may be changed. A registration statement relating to these securities has been declared effective by the Securities and Exchange Commission. We are not using this preliminary prospectus supplement together with the accompanying prospectus to offer or to sell these securities or to solicit offers to buy these securities in any place where an offer or sale is prohibited.
Subject to Completion. Dated November 10, 2015.
PRELIMINARY PROSPECTUS SUPPLEMENT (To Prospectus dated November 26, 2013) |
Filed Pursuant to Rule 424(b)(2) Registration Statement No.: 333-192551 |
AstraZeneca PLC
$
$ % Notes due 2018
$ % Notes due 2020
$ % Notes due 2025
$ % Notes due 2045
$ Floating Rate Notes due 2018
The notes offered by this prospectus supplement comprise the $ % Notes due 2018 (the “2018 Notes”), the $ % Notes due 2020 (the “2020 Notes”), the $ % Notes due 2025 (the “2025 Notes”), the $ % Notes due 2045 (the “2045 Notes” and, collectively with the 2018 Notes, the 2020 Notes and the 2025 Notes, the “Fixed Rate Notes”) and the $ Floating Rate Notes due 2018 (the “Floating Rate Notes”, and together with the Fixed Rate Notes, the “notes”). Interest on the Fixed Rate Notes will be payable semi-annually in arrears on May and November of each year, beginning May , 2016. Interest on the Floating Rate Notes will be payable quarterly in arrears on February , May , August and November of each year, beginning February , 2016.
The notes are redeemable in whole but not in part prior to their respective maturity dates upon the occurrence of certain tax events described herein. In addition, we may redeem the notes in whole or in part, at any time at the greater of 100% of the principal amount or a make-whole amount described herein, in each case, plus accrued interest.
The notes will constitute unsecured and unsubordinated indebtedness of AstraZeneca PLC and will rank equally with all other unsecured and unsubordinated indebtedness of AstraZeneca PLC from time to time outstanding.
The notes are being offered globally for sale in jurisdictions where it is lawful to make such offers and sales. We will apply to list the notes on the New York Stock Exchange.
Investing in the notes involves risks.
See “Risk Factors” beginning on page 1 of the attached prospectus.
Neither the Securities and Exchange Commission nor any other regulatory body has approved or disapproved of the notes or determined if this prospectus supplement or the accompanying prospectus is truthful or complete. Any representation to the contrary is a criminal offense.
Price to Public(1) | Underwriting Commissions | Proceeds to AstraZeneca (before expenses)(2) | |||||||
Per 2018 Note | % | % | % | ||||||
Total for 2018 Notes | $ | $ | $ | ||||||
Per 2020 Note | % | % | % | ||||||
Total for 2020 Notes | $ | $ | $ | ||||||
Per 2025 Note | % | % | % | ||||||
Total for 2025 Notes | $ | $ | $ | ||||||
Per 2045 Note | % | % | % | ||||||
Total for 2045 Notes | $ | $ | $ | ||||||
Per Floating Rate Note | % | % | % | ||||||
Total for Floating Rate Notes | $ | $ | $ | ||||||
Total | $ | $ | $ |
1 | Plus interest accrued on the notes from November , 2015, if any. |
2 | See “Underwriting” in this prospectus supplement. |
We expect to deliver the notes to investors in registered book-entry form only through the facilities of The Depository Trust Company (“DTC”) on or about November , 2015. Beneficial interests in the notes will be shown on, and transfers thereof will be effected only through, records maintained by DTC and its direct and indirect participants, including Clearstream Banking, société anonyme (“Clearstream, Luxembourg”), and Euroclear Bank SA/NV (“Euroclear”).
Joint Book-Running Managers
Barclays | BofA Merrill Lynch | HSBC | Morgan Stanley |
Co-Managers
November , 2015.
table of Contents
Page
About This Document | S-1 |
Where You Can Find More Information | S-1 |
Forward-Looking Statements | S-3 |
Summary | S-4 |
The Offering | S-5 |
Selected Financial Information | S-9 |
Use of Proceeds | S-11 |
Indebtedness and Capitalization | S-11 |
Ratio of Earnings to Fixed Charges | S-12 |
Description of Notes | S-12 |
Taxation | S-17 |
Clearance and Settlement | S-18 |
Underwriting | S-19 |
Selling Restrictions | S-21 |
Validity of Notes | S-22 |
We have not, and the underwriters have not, authorized any other person to provide you with any information other than the information contained in this prospectus supplement, the accompanying prospectus and the documents incorporated by reference herein and therein. Neither we nor the underwriters take responsibility for, or provide any assurance as to the reliability of, any different or additional information. Neither we nor the underwriters are making an offer to sell the notes in any jurisdiction where the offer or sale is not permitted. You should assume the information appearing in this prospectus supplement, the accompanying prospectus and the documents incorporated by reference herein and therein are accurate only as of their respective dates. Our business, financial condition, results of operations and prospects may have changed since those dates.
About This Document
This document is in two parts. The first part is the prospectus supplement, which describes the specific terms of the notes we are offering and certain other matters relating to us and our results of operations and financial condition. The second part, the attached prospectus, gives more general information about securities we may offer from time to time, some of which does not apply to the notes we are offering. Generally, when we refer to the prospectus, we are referring to both parts of this document combined. If the description of the notes in the prospectus supplement differs from the description in the attached prospectus, the description in the prospectus supplement supersedes the description in the attached prospectus.
Where You Can Find More Information
We file annual reports with the Securities and Exchange Commission (the “SEC”), and furnish other information on Form 6-K to the SEC. Our SEC filings are available to the public over the internet at the SEC’s website at http://www.sec.gov. You may also read and copy any document we file at the SEC’s public reference room located at 100 F Street, N.E., Room 1580, Washington, D.C. 20549. Please call the SEC at 1-800-SEC-0330 for further information on the public reference room. You may also read and copy these documents at the offices of the New York Stock Exchange, 20 Broad Street, New York, New York 10005. These documents are also available on our internet website at http://www.astrazeneca.com. The contents of our website are not incorporated into, and do not form a part of, this prospectus supplement.
S-1
INCORPORATION OF DOCUMENTS BY REFERENCE
The SEC allows us to “incorporate by reference” the information we file with or furnish to them, which means that we can disclose important information to you by referring you to those documents. The information incorporated by reference is considered to be part of this prospectus supplement and the accompanying prospectus and later information that we file with the SEC will automatically update or supersede this information. We incorporate by reference the documents listed below and any of our future filings made with the SEC under Sections 13(a), 13(c), and 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), until such time as all of the securities covered by this prospectus supplement have been sold:
· | Our Annual Report on Form 20-F for the year ended December 31, 2014 filed with the SEC on March 10, 2015. |
· | The reconciliation table under the heading “First Half” and “Second Quarter”, but only with respect to 2014 figures in our Report on Form 6-K furnished to the SEC on July 31, 2014. |
· | The reconciliation table under the heading “Third Quarter” and “Nine Months”, but only with respect to 2014 figures in our Report on Form 6-K furnished to the SEC on November 6, 2014. |
· | Our Report on Form 6-K titled “AstraZeneca Announces Positive Phase III Top-Line Results for PT003 from the Pinnacle 1 and Pinnacle 2 Studies in COPD” furnished to the SEC on March 18, 2015. |
· | Our Report on Form 6-K titled “Selumetinib Granted Orphan Drug Designation by US FDA for Treatment of Uveal Melanoma” furnished to the SEC on April 17, 2015. |
· | Our Report on Form 6-K, excluding the section titled “Independent Review Report to AstraZeneca PLC” furnished to the SEC on July 30, 2015. |
· | Our Report on Form 6-K titled “AstraZeneca Appoints Dr Sean Bohen as Executive Vice President of Global Medicines Development and Chief Medical Officer” furnished to the SEC on August 24, 2015. |
· | Our Report on Form 6-K titled “AstraZeneca and Valeant Pharmaceuticals to Partner on Brodalumab” furnished to the SEC on September 1, 2015. |
· | Our Report on Form 6-K titled “US FDA Approves Expanded Indication for Brilinta to Include Long-Term Use in Patients with a History of Heart Attack” furnished to the SEC on September 4, 2015. |
· | Our Report on Form 6-K furnished to the SEC on November 5, 2015 titled “Year-To-Date and Q3 2015 Results”. |
· | All other documents we file pursuant to Section 13(a), 13(c) or 15(d) of the Exchange Act after the date of this prospectus supplement and prior to the termination of the offering of the notes and, to the extent designated therein, reports furnished to the SEC on Form 6-K, in each case with effect from the date that such document or report is so filed or furnished. |
We will provide without charge to each person, including any beneficial owner, to whom this prospectus is delivered, upon his or her written or oral request, a copy of any or all documents referred to above which have been or may be incorporated by reference into this prospectus other than exhibits which are not specifically incorporated by reference into those documents. You can request those documents from either of the below:
AstraZeneca PLC
2 Kingdom Street
London W2 6BD
England
The Company Secretary
Tel. No.: +44-20-7604-8000
Investor Relations
Tel. No.: +44-20-7604-8000
S-2
Forward-Looking Statements
From time to time, we may make statements regarding our assumptions, projections, expectations, intentions or beliefs about future events. These statements constitute “forward-looking statements” for purposes of the US Private Securities Litigation Reform Act of 1995. We caution that these statements may and often do vary from actual results and the differences between these statements and actual results can be material. Accordingly, we cannot assure you that actual results will not differ materially from those expressed or implied by the forward-looking statements. You should read the section entitled “Cautionary statement regarding forward-looking statements” in our annual report on Form 20-F for the year ended December 31, 2014, in our Report on Form 6-K dated November 5, 2015 and the section entitled “Forward-Looking Statements” on pages 3 and 4 of the attached prospectus for additional information.
We undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. In light of these risks, uncertainties and assumptions, the forward-looking events discussed in this prospectus supplement, the attached prospectus or the information incorporated by reference, might not occur.
S-3
Summary
Unless otherwise stated in this prospectus supplement or unless the context otherwise requires, the words “Company”, “we”, “our” and “us” refer to AstraZeneca PLC.
The following summary contains basic information about this offering. It may not contain all the information that is important to you. The Description of Notes section of this prospectus supplement and the Description of Debt Securities section of the attached prospectus contain more detailed information regarding the terms and conditions of the notes. The following summary is qualified in its entirety by reference to the detailed information appearing elsewhere or incorporated by reference in this prospectus supplement and in the attached prospectus.
Overview
We are a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for three main therapy areas of healthcare: cardiovascular and metabolic diseases; oncology; and respiratory, inflammation and autoimmunity.
Backed by a track record of pharmaceutical innovation over more than 70 years, we have a broad range of marketed medicines that continue to make a positive difference in healthcare. In addition to our pipeline of products in the discovery and development phases, our pipeline includes lifecycle management initiatives for approved products to bring further benefit for patients and maximize their commercial potential. As of December 31, 2014, our range of medicines included four products with annual sales of over $1 billion each.
We have activities in over 100 countries worldwide, with major research and development centers in four countries, including China, Sweden, the United Kingdom and the United States, and manufacturing facilities in 17 countries. We employ approximately 57,500 people (approximately 37% in Europe, the Middle East and Africa, 30% in the Americas and 33% in Asia-Pacific) and have a growing presence in important emerging markets, including China. Our principal executive office is located at 2 Kingdom Street, London W2 6BD and our telephone number is +44-20-7604-8000.
Our ADSs are listed on the New York Stock Exchange under the symbol “AZN”. Our ordinary shares are admitted to trading on the London Stock Exchange under the symbol “AZN” and are also listed on the Stockholm Stock Exchange under the symbol “AZN”.
Recent Developments
On November 6, 2015, AstraZeneca announced that it had entered into a definitive agreement to acquire ZS Pharma, a biopharmaceutical company based in San Mateo, California. ZS Pharma uses its proprietary ion trap technology to develop novel treatments for hyperkalaemia, a serious condition of elevated potassium in the bloodstream, typically associated with chronic kidney disease (“CKD”) and chronic heart failure (“CHF”).
The transaction will give AstraZeneca access to the potassium-binding compound ZS-9, a potential best-in-class treatment for hyperkalaemia, a condition associated with increased mortality in CKD and CHF. ZS-9 is under regulatory review by the US Food and Drug Administration with a Prescription Drug User Fee Act goal date of May 26, 2016. A submission for European Marketing Application Authorization is planned by the end of 2015. Pending and granted patents, some of which are under license, have expiries out to 2032 and beyond.
The acquisition continues AstraZeneca's strategy of targeted business development with a focus on three main therapy areas. AstraZeneca believes that ZS Pharma represents a strong fit with AstraZeneca's pipeline and portfolio in Cardiovascular & Metabolic Disease, one of the company’s three main therapy areas. ZS-9 complements the company's increasing focus on CKD and CHF, including the investigational medicine roxadustat, which is currently in Phase III development for patients with anaemia associated with CKD, as well as its leading diabetes portfolio.
Under the terms of the agreement, AstraZeneca will acquire all of the outstanding capital stock of ZS Pharma for $90 per share in an all-cash transaction, or approximately $2.7 billion in aggregate transaction value.
S-4
Subject to customary conditions, including the tender of a majority of the outstanding ZS Pharma shares and the expiration or earlier termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, the transaction is expected to close by the end of 2015.
Upon completion, ZS Pharma, which has around 200 employees across three sites in California, Texas and Colorado, will become a wholly owned subsidiary of AstraZeneca.
S-5
The Offering | |
Issuer | AstraZeneca PLC |
Notes Being Offered |
$ aggregate principal amount of % Notes due 2018 (the “2018 Notes”)
$ aggregate principal amount of % Notes due 2020 (the
“2020 Notes”)
$ aggregate principal amount of % Notes due 2045 (the “2045 Notes”)
The 2018 Notes, the 2020 Notes, the 2025 Notes and the 2045 Notes are collectively referred to herein as the “Fixed Rate Notes”.
$ aggregate principal amount of Floating Rate Notes due 2018 (the “Floating Rate Notes”)
We refer to the Floating Rate Notes and the Fixed Rate Notes in this prospectus supplement as the “notes”.
The notes will be issued under an indenture dated as of April 1, 2004 (the “Indenture”) between us and The Bank of New York Mellon (formerly known as The Bank of New York), as successor trustee to JPMorgan Chase Bank, and the terms of the securities will be set forth in an Officer’s Certificate to be dated November , 2015. The 2018 Notes, the 2020 Notes, the 2025 Notes, the 2045 Notes and the Floating Rate Notes will each be treated as a separate series of notes and, as such, will vote and act, and may be redeemed, separately.
|
PROVISIONS APPLICABLE TO THE FIXED RATE NOTES | |
Maturity |
2018 Notes: November , 2018
2020 Notes: November , 2020
2025 Notes: November , 2025
2045 Notes: November , 2045
|
Interest Rate
|
The 2018 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually.
The 2020 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually.
The 2025 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually.
The 2045 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually. |
S-6
The 2025 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually.
The 2045 Notes will bear interest from November , 2015 at a fixed rate of % per annum, payable semi-annually.
| |
Interest Payment Dates . | Interest on the Fixed Rate Notes will be paid semi-annually in arrears on May and November of each year, commencing May , 2016 (each, a “Fixed Rate Interest Payment Date”).
|
Interest Periods | The first interest period for the Fixed Rate Notes will be the period from and including the issue date to but excluding the first Fixed Rate Interest Payment Date. Thereafter, the interest periods for the Fixed Rate Notes will be the periods from and including the Fixed Rate Interest Payment Dates to but excluding the immediately succeeding Fixed Rate Interest Payment Date (together with the first interest period, each a “Fixed Rate Interest Period”). The final Fixed Rate Interest Period will be the period from and including the Fixed Rate Interest Payment Date immediately preceding the maturity date to the maturity date.
|
Day count fraction | 360-day year and twelve 30-day months.
|
Optional Make-Whole Redemption |
We may redeem the Fixed Rate Notes, in whole or in part, at any time and from time to time, at a redemption price equal to the greater of (1) 100% of the principal amount of the Fixed Rate Notes plus accrued interest to the date of redemption and (2) as determined by the Quotation Agent, the sum of the present values of the remaining scheduled payments of principal and interest on the applicable Fixed Rate Notes (excluding any portion of such payments of interest accrued and unpaid as of the date of redemption) discounted to the redemption date on a semiannual basis (assuming a 360-day year consisting of twelve 30-day months) at the treasury rate, plus the make-whole spread as set forth below (the “Make-Whole Spread”) plus, in each case, accrued interest thereon to the date of redemption.
See “Description of Notes — Redemption — Optional Redemption”.
|
Make-Whole Spread |
2018 Notes: basis points.
2020 Notes: basis points.
2025 Notes: basis points.
2045 Notes: basis points.
|
S-7
PROVISIONS APPLICABLE TO THE FLOATING RATE NOTES | |
Maturity | November , 2018 |
Interest Rate | The interest rate for the Floating Rate Notes for the first interest period will be LIBOR (as defined herein) as determined on November , 2015 plus the Spread. Thereafter, the interest rate for any Floating Rate Interest Period (as defined below) will be LIBOR as determined on the applicable Interest Determination Date (as defined below) plus the Spread. |
Spread | basis points. |
Interest Payment Dates | Interest on the Floating Rate Notes will be paid quarterly in arrears on February , May , August and November of each year, commencing February , 2016 (each, a “Floating Rate Interest Payment Date”). |
Interest Reset Dates | Interest on the Floating Rate Notes will have Interest Reset Dates of February , May , August and November of each year, commencing February , 2016 |
Interest Periods | The first interest period for the Floating Rate Notes will be the period from and including the original issue date to but excluding the immediately succeeding Interest Reset Date. Thereafter, the interest periods for the Floating Rate Notes will be the periods from and including an Interest Reset Date to but excluding the immediately succeeding Interest Reset Date (together with the first interest period, each a “Floating Rate Interest Period”). However, the final Floating Rate Interest Period will be the period from and including the Interest Reset Date immediately preceding the maturity date to the maturity date. |
Interest Determination Dates | Interest for the Floating Rate Notes will be determined two London business days prior to each Interest Reset Date. |
Day Count Fraction | 360-day year and actual number of days elapsed. |
Redemption | Subject to the optional tax redemption described below, we may not redeem the Floating Rate Notes prior to maturity. |
PROVISIONS APPLICABLE TO ALL OF THE NOTES | |
Optional Tax Redemption | In the event of various tax law changes and other limited circumstances that require us to pay additional amounts as described under “Description of Notes — Redemption — Optional Tax Redemption”, we may redeem in whole, but not in part, any series of the notes prior to maturity at a redemption price equal to 100% of their principal amount plus accrued interest to the date of redemption. |
S-8
Payment of Additional Amounts | For more information on additional amounts and the situations in which AstraZeneca PLC may be required to pay additional amounts, see “Description of Notes —Payment of Additional Amounts” in this prospectus supplement. |
Regular Record Dates for Interest | The 15th calendar day preceding each Fixed Rate Interest Payment Date or Floating Rate Interest Payment Date, as the case may be, whether or not such day is a business day. |
Ranking | The notes will constitute unsecured and unsubordinated indebtedness of AstraZeneca PLC and will rank equally with all other existing and future unsecured and unsubordinated indebtedness of AstraZeneca PLC. |
Form, Denomination, Clearance and Settlement | We will issue the notes in fully registered form in denominations of $2,000 and integral multiples of $1,000 in excess thereof. Each series of notes will be represented by one or more global securities registered in the name of a nominee of DTC. You will hold beneficial interests in your respective series of notes through DTC and DTC and its direct and indirect participants (including Clearstream, Luxembourg and Euroclear) will record your beneficial interest on their books. We will not issue certificated notes except in limited circumstances that we explain under “Legal Ownership — Global Securities — Special situations when the global security will be terminated” in the attached prospectus. Settlement of the notes will occur through DTC in same day funds. For information on DTC’s book-entry system, see “Clearance and Settlement — The Clearing Systems — DTC” in the attached prospectus. |
Governing Law | The notes will be governed by the laws of the State of New York. |
Listing | We will apply to list the notes on the New York Stock Exchange. |
Sinking fund | There is no sinking fund for any series of notes. |
Restrictive covenants | The Indenture contains covenants restricting our ability to enter into sale and leaseback transactions, pledge our assets to secure certain borrowings and create or incur liens on our property. These restrictive covenants are described in the attached prospectus under the heading “Description of Debt Securities — Covenants”. |
S-9
Defeasance | Each series of notes will be subject to the defeasance and covenant defeasance provisions in the Indenture described under “Description of Debt Securities — Satisfaction, Discharge and Defeasance” in the attached prospectus.
|
Further Issuances |
We may, at our option, at any time and without the consent of the then existing noteholders, reopen any series of notes and issue additional notes in one or more transactions after the date of this prospectus supplement with terms (other than the issuance date and, possibly, the first interest payment date and issue price) identical to such series of notes issued hereby. These additional notes will be deemed to have been part of the applicable series of notes offered hereby and will provide the holders of these additional notes the right to vote together with holders of the applicable series of notes issued hereby.
We may offer additional notes of any series with original issue discount (“OID”) for US federal income tax purposes as part of a further issue. Purchasers of notes of such series after the date of any further issue will not be able to differentiate between notes sold as part of such further issue and previously issued notes. If we were to issue additional notes with OID, purchasers of notes after such further issue may be required to accrue OID with respect to their notes. This may affect the price of outstanding notes of such series following a further issue. Purchasers are advised to consult legal counsel with respect to the implications of any future decision by us to undertake a further issue of notes of any series with OID.
|
Use of Proceeds |
We expect to receive approximately $ from the sale of the notes, after deducting underwriting discounts and other expenses related to this offering.
We intend to use the net proceeds from this offering to fund our acquisition of ZS Pharma, to repay certain of our outstanding commercial paper obligations and for general corporate purposes. See “Summary—Recent Developments”.
|
Trustee, Calculation Agent and Paying Agent | The Bank of New York Mellon, as successor trustee to JPMorgan Chase Bank and as calculation agent under the Calculation Agency Agreement to be dated as of November , 2015. |
Timing and Delivery | We currently expect delivery of the notes to occur on November , 2015. |
Risk Factors | You should carefully consider all of the information in this prospectus supplement and the attached prospectus, which includes information incorporated |
S-10
by reference. In particular, you should evaluate the specific factors under “Risk Factors” beginning on page 1 of the attached prospectus, as well as those discussed under the heading “Risk Factors” in our Annual Report on Form 20-F for the year ended December 31, 2014 and under the heading “Principal Risks and Uncertainties” of our Report on Form 6-K furnished to the SEC on November 5, 2015, each of which is incorporated by reference in this prospectus supplement, for risks involved with an investment in the notes. |
S-11
Selected Financial Information
The selected consolidated financial data for AstraZeneca PLC set forth below as of and for the years ended December 31, 2014, 2013, 2012, 2011 and 2010 is derived from our audited consolidated financial statements and has been prepared in accordance with International Financial Reporting Standards (“IFRS”) as adopted by the European Union and as issued by the International Accounting Standards Board. The selected consolidated financial data set forth below as of and for the nine-month periods ended September 30, 2015 and 2014 is derived from our unaudited consolidated financial statements for the nine-month period ended September 30, 2015 contained in our Report on Form 6-K dated November 5, 2015. The unaudited consolidated financial statements include all adjustments which we consider necessary for a fair statement of our financial position and results of operations for those periods in accordance with IFRS. The results for the nine-month period ended September 30, 2015 are not necessarily indicative of the results that might be expected for the entire year ending December 31, 2015 or any other period. The selected consolidated financial information set forth below should be read in conjunction with our consolidated financial statements, the notes related thereto and the financial and operating data incorporated by reference into this prospectus supplement and the accompanying prospectus.
For the Nine Months Ended September 30, | For the Year Ended December 31, | |||||||||||||||||||||||||||
2015 | 2014 | 2014 | 2013 | 2012 | 2011 | 2010 | ||||||||||||||||||||||
(In $ millions, except per share amounts) | ||||||||||||||||||||||||||||
Income Statement Data | ||||||||||||||||||||||||||||
Total Revenue | 18,309 | 19,831 | 26,095 | 25,711 | 27,973 | 33,591 | 33,269 | |||||||||||||||||||||
Cost of sales | (3,377 | ) | (4,175 | ) | (5,842 | ) | (5,261 | ) | (5,393 | ) | (6,026 | ) | (6,389 | ) | ||||||||||||||
Distribution costs | (240 | ) | (236 | ) | (324 | ) | (306 | ) | (320 | ) | (346 | ) | (335 | ) | ||||||||||||||
Research and development | (4,251 | ) | (4,080 | ) | (5,579 | ) | (4,821 | ) | (5,243 | ) | (5,523 | ) | (5,318 | ) | ||||||||||||||
Selling, general and administrative costs | (8,444 | ) | (8,916 | ) | (13,000 | ) | (12,206 | ) | (9,839 | ) | (11,161 | ) | (10,445 | ) | ||||||||||||||
Profit on disposal of subsidiary(1) | — | — | — | — | — | 1,483 | — | |||||||||||||||||||||
Other operating income and expense | 1,029 | 62 | 787 | 595 | 970 | 777 | 712 | |||||||||||||||||||||
Operating profit | 3,026 | 2,486 | 2,137 | 3,712 | 8,148 | 12,795 | 11,494 | |||||||||||||||||||||
Finance income | 33 | 45 | 78 | 50 | 42 | 50 | 516 | |||||||||||||||||||||
Finance expense | (783 | ) | (703 | ) | (963 | ) | (495 | ) | (544 | ) | (562 | ) | (1,033 | ) | ||||||||||||||
Share of after tax losses in Joint Ventures | (9 | ) | (2 | ) | (6 | ) | — | — | — | — | ||||||||||||||||||
Profit before tax | 2,267 | 1,826 | 1,246 | 3,267 | 7,646 | 12,283 | 10,977 | |||||||||||||||||||||
Taxation | (249 | ) | (270 | ) | (11 | ) | (696 | ) | (1,376 | ) | (2,333 | ) | (2,896 | ) | ||||||||||||||
Profit for the period | 2,018 | 1,556 | 1,235 | 2,571 | 6,270 | 9,950 | 8,081 | |||||||||||||||||||||
Profit attributable to: | ||||||||||||||||||||||||||||
Equity holders of the Company | 2,017 | 1,554 | 1,233 | 2,556 | 6,240 | 9,917 | 8,053 | |||||||||||||||||||||
Non-controlling interests | 1 | 2 | 2 | 15 | 30 | 33 | 28 | |||||||||||||||||||||
Dividends declared and paid in the period per share | $ | 0.90 | $ | 0.90 | $ | 2.80 | $ | 2.80 | $ | 2.85 | $ | 2.70 | $ | 2.41 | ||||||||||||||
S-12
For
the Nine Months Ended September 30, | For the Year Ended December 31, | |||||||||||||||||||||||
2015 | 2014 | 2013 | 2012 | 2011 | 2010 | |||||||||||||||||||
(In $ millions) | ||||||||||||||||||||||||
Balance Sheet Data | ||||||||||||||||||||||||
Property, plant and equipment, goodwill and intangible assets | 37,632 | 38,541 | 31,846 | 32,435 | 27,267 | 28,986 | ||||||||||||||||||
Investments in joint ventures | 48 | 59 | — | — | — | — | ||||||||||||||||||
Other investments | 444 | 502 | 281 | 199 | 201 | 211 | ||||||||||||||||||
Derivative financial instruments | 479 | 465 | 365 | 389 | 342 | 324 | ||||||||||||||||||
Other receivables | 925 | 1,112 | 1,867 | 352 | — | — | ||||||||||||||||||
Deferred tax assets | 1,391 | 1,219 | 1,205 | 1,111 | 1,514 | 1,475 | ||||||||||||||||||
Current assets | 13,199 | 16,697 | 20,335 | 19,048 | 23,506 | 25,131 | ||||||||||||||||||
Total assets | 54,118 | 58,595 | 55,899 | 53,534 | 52,830 | 56,127 | ||||||||||||||||||
Current liabilities | (16,036 | ) | (17,330 | ) | (16,051 | ) | (13,903 | ) | (15,752 | ) | (16,787 | ) | ||||||||||||
Non-current liabilities | (20,714 | ) | (21,619 | ) | (16,595 | ) | (15,685 | ) | (13,612 | ) | (15,930 | ) | ||||||||||||
Net assets | 17,368 | 19,646 | 23,253 | 23,946 | 23,466 | 23,410 | ||||||||||||||||||
Share capital | 316 | 316 | 315 | 312 | 323 | 352 | ||||||||||||||||||
Reserves attributable to equity holders | 17,033 | 19,311 | 22,909 | 23,419 | 22,917 | 22,861 | ||||||||||||||||||
Non-controlling interests | 19 | 19 | 29 | 215 | 226 | 197 | ||||||||||||||||||
Total equity and reserves | 17,368 | 19,646 | 23,253 | 23,946 | 23,466 | 23,410 | ||||||||||||||||||
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Use of Proceeds
We estimate that the net proceeds from this offering, after deducting the underwriters’ discount and estimated offering expenses payable by us, will be approximately $ .
We intend to use the net proceeds from this offering to fund our acquisition of ZS Pharma, to repay certain of our outstanding commercial paper obligations and for general corporate purposes. See “Summary—Recent Developments”.
Indebtedness and Capitalization
The following table sets forth our indebtedness and capitalization as at September 30, 2015 and as adjusted to reflect the issuance of the notes. The data included in the table below is prepared on the basis of IFRS.
This table should be read in conjunction with our audited and unaudited consolidated financial statements, the notes related thereto and the financial and operating data incorporated by reference into this prospectus supplement and the accompanying prospectus.
As of September 30, 2015 | As Adjusted | |||||||
(Unaudited) | ||||||||
(In $ millions) | (In $ millions) | |||||||
Current loans and borrowings | ||||||||
Short-term borrowings | 2,314 | |||||||
Current installments of loans | 63 | |||||||
Overdrafts | 294 | |||||||
Total | 2,671 | |||||||
Non-current loans and borrowings | ||||||||
Interest-bearing loans and borrowings | 8,276 | |||||||
Notes offered hereby | — | |||||||
Total | 8,276 | |||||||
Equity | ||||||||
Share capital | 316 | |||||||
Share premium account | 4,291 | |||||||
Other reserves | 2,035 | |||||||
Retained earnings | 10,707 | |||||||
Total | 17,349 | |||||||
Non-controlling interests | 19 | |||||||
Total | 17,368 | |||||||
Total capitalization | 25,644 |
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Ratio of Earnings to Fixed Charges
Our consolidated ratios of earnings to fixed charges calculated in accordance with IFRS for the years ended December 31, 2014, 2013, 2012, 2011 and 2010 and for the nine-month period ended September 30, 2015 are as follows:
Nine Months Ended September 30, | Year Ended December 31, | |||||||||||||||||||||
2015 | 2014 | 2013 | 2012 | 2011 | 2010 | |||||||||||||||||
(unaudited) | ||||||||||||||||||||||
11.7 | 6.1 | 9.9 | 19.9 | 29.5* | 25.2* |
For the purpose of computing these ratios, earnings consist of the income from continuing ordinary activities before taxation of AstraZeneca group companies and income received from companies owned 50% or less, plus fixed charges. Fixed charges consist of interest on all indebtedness, amortization of debt discount and expense and that portion of rental expense representative of the interest factor.
* Restated following the adoption of IAS
19 (2011) as detailed in the Group Accounting Policies from page 136 of the Company’s Annual Report and Form 20-F Information
2013, included in exhibit 15.1 to the Company’s Form 20-F dated March 20, 2014.
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Description of Notes
This section describes the specific financial and legal terms of the notes and supplements the more general description under “Description of Debt Securities” in the attached prospectus. To the extent that the following description is inconsistent with the terms described under “Description of Debt Securities” in the attached prospectus, the following description replaces that in the attached prospectus.
General
We will offer $ initial aggregate principal amount of % Notes due 2018 (the “2018 Notes”), $ initial aggregate principal amount of % Notes due 2020 (the “2020 Notes”), $ initial aggregate principal amount of % Notes due 2025 (the “2025 Notes”), $ initial aggregate principal amount of % Notes due 2045 (the “2045 Notes” and, collectively with the 2018 Notes, the 2020 Notes and the 2025 Notes, the “Fixed Rate Notes”) and $ initial aggregate principal amount of Floating Rate Notes due 2018 (the “Floating Rate Notes”, and together with the Fixed Rate Notes, the “notes”), each as a separate series of notes under the Indenture, and, as such, each series of notes will vote and act, and may be redeemed, separately. The notes will be governed by New York law.
The notes will be unsecured, unsubordinated indebtedness of AstraZeneca PLC and will rank equally with all of AstraZeneca PLC’s other unsecured and unsubordinated indebtedness from time to time outstanding.
There is no sinking fund for any series of notes. We will apply to list the notes on the New York Stock Exchange.
Interest Payments and Maturity
For purposes of the description below, “business day” means any day which is not, in London, England or New York, New York, or the place of payment of amounts payable in respect of the notes, a Saturday, a Sunday, a legal holiday or a day on which banking institutions are authorized or obligated by law, regulation or executive order to close. A “London business day” is a day on which dealings in deposits in U.S. dollars are transacted in the London interbank market.
Fixed Rate Notes
Maturity. The entire principal amount of the 2018 Notes, the 2020 Notes, the 2025 Notes and the 2045 Notes will mature and become due and payable, together with any accrued and unpaid interest, on November , 2018, November , 2020, November , 2025 and November , 2045, respectively.
Interest Rate. Each of the 2018 Notes, the 2020 Notes, the 2025 Notes and the 2045 Notes will bear interest from their respective original issue date until their principal amount is paid or made available for payment, at a rate equal to %, %, % and % per annum, respectively, calculated on the basis of a 360-day year and twelve 30-day months.
Interest Payment Dates. Interest on the Fixed Rate Notes will be paid semi-annually in arrears on May and November of each year, commencing May , 2016 (each a “Fixed Rate Interest Payment Date”). However, if a Fixed Rate Interest Payment Date would fall on a day that is not a business day, the Fixed Rate Interest Payment Date will be postponed to the next succeeding day that is a business day, but no additional interest shall be paid unless we fail to make payment on such date.
Interest Periods. The first interest period for the Fixed Rate Notes will be the period from and including the issue date to but excluding the first Fixed Rate Interest Payment Date. Thereafter, the interest periods for the Fixed Rate Notes will be the periods from and including the Fixed Rate Interest Payment Dates to but excluding the immediately succeeding Fixed Rate Interest Payment Date (together with the first interest period, each a “Fixed Rate Interest Period”). The final Fixed Rate Interest Period will be the period from and including the Fixed Rate Interest Payment Date immediately preceding the maturity date to the maturity date.
Floating Rate Notes
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Maturity. The entire principal amount of the Floating Rate Notes will mature and become due and payable, together with any accrued and unpaid interest, on November , 2018.
Interest Rate. The interest rate for the Floating Rate Notes for the first Floating Rate Interest Period (as defined below) will be LIBOR (as defined below) as determined on November , 2015 plus the Spread. Thereafter, the interest rate for each Floating Rate Interest Period other than the first Floating Rate Interest Period will be LIBOR as determined on the applicable Interest Determination Date (as defined below) plus the Spread, in each case calculated on the basis of a 360-day year and the actual number of days elapsed. The Spread is basis points for the Floating Rate Notes.
Interest Payment Dates. Interest on the Floating Rate Notes will be paid quarterly in arrears on February , May , August and November of each year, commencing February , 2016 (each a “Floating Rate Interest Payment Date”). However, if a Floating Rate Interest Payment Date would fall on a day that is not a business day, the Floating Rate Interest Payment Date will be postponed to the next succeeding day that is a business day, except that if the business day falls in the next succeeding calendar month, the applicable Floating Rate Interest Payment Date will be the immediately preceding business day. In each such case, except for the Floating Rate Interest Payment Date falling on the maturity date, the Floating Rate Interest Periods (as defined below) and the Interest Reset Dates will be adjusted accordingly to calculate the amount of interest payable on the Floating Rate Notes.
Interest Reset Dates. The interest rate will be reset on February , May , August and November of each year, commencing February , 2016 (each, an “Interest Reset Date”). However, if any Interest Reset Date would otherwise be a day that is not a business day, that Interest Reset Date will be postponed to the next succeeding day that is a business day, except that if the business day falls in the next succeeding calendar month, the applicable Interest Reset Date will be the immediately preceding business day.
Interest Periods. The first interest period will be the period from and including the original issue date to but excluding the immediately succeeding Interest Reset Date. Thereafter, the interest periods will be the periods from and including an Interest Reset Date to but excluding the immediately succeeding Interest Reset Date (together with the first interest period, each a “Floating Rate Interest Period”). However, the final Interest Period will be the period from and including the Interest Reset Date immediately preceding the maturity date to the maturity date.
Interest Determination Date. The calculation agent in respect of the Floating Rate Notes, will determine LIBOR (as defined below) for each Floating Rate Interest Period on the second London business day prior to the first day of such Floating Rate Interest Period (an “Interest Determination Date”). LIBOR for the first Floating Rate Interest Period will be determined on November , 2015.
“LIBOR” means, with respect to any Interest Determination Date, the offered rate for deposits of US dollars having a maturity of three months that appears on the Reuters Screen LIBOR01 display page, or any successor page, on Reuters or any successor service (or any such other service(s) as may be nominated by ICE Benchmark Administration Limited (“IBA”) or its successor or such other entity assuming the responsibility of IBA or its successor in calculating the London Interbank Offered Rate in the event IBA or its successor no longer does so) (the “Designated LIBOR Page”).
If no rate appears on the Designated LIBOR Page, LIBOR will be determined for such Interest Determination Date on the basis of the rates at approximately 11:00 a.m., London time, on such Interest Determination Date at which deposits in US dollars are offered to prime banks in the London inter-bank market by four major banks in such market selected by the calculation agent, after consultation with us, for a term of three months and in a principal amount equal to an amount that in the judgment of the calculation agent is representative for a single transaction in US dollars in such market at such time (a “Representative Amount”). The calculation agent will request the principal London office of each of such banks to provide a quotation of its rate. If at least two such quotations are provided, LIBOR for such Floating Rate Interest Period will be the arithmetic mean (rounded, if necessary, to the nearest one-hundred-thousandth of a percentage point, with five-millionths of a percentage point rounded upwards) of such quotations. If fewer than two such quotations are provided, LIBOR for such Floating Rate Interest Period will be the arithmetic mean (rounded, if necessary, to the nearest one-hundred-thousandth of a percentage point, with five millionths of a percentage point rounded upwards) of the rates quoted at approximately 11:00 a.m. in the City of New York on such Interest Determination Date by three major banks in New York City, selected by the calculation agent, after consultation with us, for loans in US dollars to leading European banks, for a term of three months and in a Representative Amount; provided, however, that if the banks so selected are not
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quoting as mentioned above, the then-existing LIBOR rate will remain in effect for such Floating Rate Interest Period.
The interest rate on the Floating Rate Notes will in no event be higher than the maximum rate permitted by law.
Redemption
As explained below, under certain circumstances we may redeem the notes before they mature. This means that we may repay them early. If we redeem one series of notes we will have no obligation to redeem any other series. You have no right to require us to redeem the notes. Notes will stop bearing interest on the redemption date, even if you do not collect your money. We will give notice to DTC of any redemption we propose to make at least 30 days, but no more than 60 days, before the redemption date. Notice by DTC to participating institutions and by these participants to street name holders of indirect interests in the notes will be made according to arrangements among them and may be subject to statutory or regulatory requirements. Subject to the optional tax redemption described below, we may not redeem the Floating Rate Notes prior to maturity.
Optional Redemption
We may redeem the Fixed Rate Notes, in whole or in part, at any time and from time to time at a redemption price equal to the greater of (i) 100% of the principal amount of such series of Fixed Rate Notes, and (ii) as determined by the Quotation Agent, the sum of the present values of the remaining scheduled payments of principal and interest on the series of Fixed Rate Notes to be redeemed (not including any portion of such payments of interest accrued as of the date of redemption) discounted to the date of redemption on a semiannual basis (assuming a 360-day year consisting of twelve 30-day months) at the treasury rate plus the Make-Whole Spread (as set forth below) plus, in each case, accrued interest thereon to the date of redemption. In connection with such optional redemption, the following defined terms apply:
· | “Treasury rate” means, with respect to any redemption date, the rate per annum equal to the semiannual equivalent yield to maturity of the comparable treasury issue, assuming a price for the comparable treasury issue (expressed as a percentage of its principal amount) equal to the comparable treasury price for such redemption date. |
· | “Comparable treasury issue” means the United States Treasury security selected by the Quotation Agent as having a maturity comparable to the remaining term of the applicable series of Fixed Rate Notes to be redeemed that would be utilized, at the time of selection and in accordance with customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of such series of Fixed Rate Notes. |
· | “Comparable treasury price” means, with respect to any redemption date, (i) the average, as determined by the Quotation Agent, of the reference treasury dealer quotations for such redemption date, after excluding the highest and lowest such reference treasury dealer quotations, or (ii) if the Quotation Agent obtains fewer than three such reference treasury dealer quotations, the average of all such quotations. |
· | “Quotation Agent” means the reference treasury dealer appointed by us. |
· | “Reference treasury dealer” means (i) each of Barclays Capital Inc., HSBC Securities (USA) Inc., Merrill Lynch, Pierce, Fenner & Smith Incorporated and Morgan Stanley & Co. LLC, and their respective successors or affiliates; provided, however, that if the foregoing shall cease to be a primary US government securities dealer in New York City (a “primary treasury dealer”), we shall substitute therefor another primary treasury dealer; and (ii) any other primary treasury dealer selected by us. |
· | “Reference treasury dealer quotations” means, with respect to each reference treasury dealer and any redemption date, the average, as determined by the Quotation Agent, of the bid and asked prices for the comparable treasury issue (expressed in each case as a percentage of its principal amount) quoted in writing to the trustee by such reference treasury dealer at 5:00 p.m., Eastern Standard Time, on the third business day preceding such redemption date. |
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· | “Make-Whole Spread” means, with respect to, (i) the 2018 Notes, basis points, (ii) the 2020 Notes, basis points, (iii) the 2025 Notes, basis points and (iv) the 2045 Notes, basis points. |
Optional Tax Redemption
In the event of various tax law changes after the date of this prospectus supplement and other limited circumstances that require us to pay additional amounts, as described below under “— Payment of Additional Amounts”, we may redeem all, but not less than all, of each series of notes at a price equal to 100% of the principal amount of each series of notes plus accrued interest to the date of redemption. This means we may repay any one or each series of notes early. We discuss our ability to redeem the notes in greater detail under “Description of Debt Securities — Optional Tax Redemption” in the accompanying prospectus.
Further Issuances
We may, without the consent of the holders of any series of notes, issue additional notes of each or any such series having the same ranking and same interest rate, maturity date, redemption terms and other terms as the applicable series of notes described in this prospectus supplement. Any such additional notes, together with the applicable series of notes offered by this prospectus supplement, will constitute a single series of securities under the Indenture. There is no limitation on the amount of notes or other debt securities that we may issue under such indenture.
We may offer additional notes of any series of notes with OID for US federal income tax purposes as part of a further issue. Purchasers of notes of such series after the date of any further issue will not be able to differentiate between notes sold as part of such further issue and previously issued notes. If we were to issue additional notes with OID, purchasers of notes after such further issue may be required to accrue OID with respect to their notes. This may affect the price of outstanding notes of such series following a further issue. Purchasers are advised to consult legal counsel with respect to the implications of any future decision by us to undertake a further issue of notes of any series with OID.
Form, Denomination, Clearance and Settlement
We will issue the notes in fully registered form. Each series of notes will be represented by one or more global securities registered in the name of a nominee of DTC. You will hold beneficial interests in the notes through DTC in book-entry form. The notes will be issued in minimum denominations of $2,000 and in integral multiples of $1,000 in excess thereof. The underwriters expect to deliver the notes through the facilities of DTC on November , 2015. Indirect holders trading their beneficial interests in the notes through DTC must trade in DTC’s same-day funds settlement system and pay in immediately available funds. Secondary market trading through Euroclear and Clearstream, Luxembourg will occur in the ordinary way following the applicable rules and operating procedures of Euroclear and Clearstream, Luxembourg. See “Clearance and Settlement” in the attached prospectus for more information about these clearing systems.
Payment of principal of and interest on each series of notes, so long as the notes are represented by global securities, as discussed below, will be made in immediately available funds. Beneficial interests in the global securities will trade in the same-day funds settlement system of DTC, and secondary market trading activity in such interests will therefore settle in same-day funds.
Payment of Additional Amounts
We agree that any amounts to be paid by us under the notes of principal, premium and interest in respect of the notes will be paid without deduction or withholding for, any and all present and future taxes, levies, duties, assessments, imposts or other governmental charges of whatever nature imposed, assessed, levied or collected by or for the account of the government of any jurisdiction in which we are resident for tax purposes (presently, the UK) or any political subdivision or taxing authority of such jurisdiction, unless such withholding or deduction is required by law. If such deduction or withholding is at any time required, we will (subject to compliance by you with any relevant administrative requirements) pay such additional amounts as will result in the receipt of such amounts as would have been received by the holder had no such withholding or deduction been required, provided that we will not have to pay additional amounts if:
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(i) the tax, levy, impost or other governmental charge would not have been imposed, assessed, levied or collected but for the holder’s connection to the jurisdiction in which we are resident for tax purposes, other than by merely holding the note or by receiving principal, premium, if any, or interest, if any, on the note, or enforcing the note. These connections include where the holder or related party:
· | is or has been a domiciliary, national or resident of such jurisdiction; |
· | is or has been engaged in a trade or business in such jurisdiction; |
· | has or had a permanent establishment in such jurisdiction; or |
· | is or has been physically present in such jurisdiction. |
(ii) the tax, levy, impost or other governmental charge would not have been imposed, assessed, levied or collected but for presentation of the note for payment, if presentation is required, more than 30 days after the security became due or payment was provided for;
(iii) the tax, levy, impost or other governmental charge is an estate, inheritance, gift, sale, transfer, personal property or similar tax, levy, impost or other governmental charge;
(iv) the tax, levy, impost or other governmental charge is payable in a manner that does not involve deduction or withholding from payments on or in respect of the relevant note;
(v) the tax, levy, impost or other governmental charge would not have been imposed or withheld but for the failure of the holder or beneficial owner to comply with any certification, identification or other reporting requirement concerning the nationality, residence, identity or connection with any jurisdiction in which we are resident for tax purposes, as required by any treaty, statute, regulation or administrative practice of such jurisdiction as a condition to relief or exemption from such tax, levy, impost or other governmental charge;
(vi) the tax, levy, impost or other governmental charge is required to be made pursuant to the European Union Directive 2003/48/EC on the taxation of savings or any other directive amending, supplementing or replacing such Directive or any law implementing or complying with, or introduced in order to conform to, such Directive or directives;
(vii) the holder would have been able to avoid such withholding or deduction by authorizing the paying agent to report information in accordance with the procedure laid down by the relevant tax authority or by producing, in the form required by the relevant tax authority, a declarative, claim, certificate, document or other evidence establishing exemption therefrom;
(viii) the holder would have been able to avoid such withholding or deduction by presenting the relevant note to another paying agent in a Member State of the EU or elsewhere;
(ix) the tax, levy, impost or other governmental charge is required by Sections 1471 through 1474 of the Code (“FATCA”), any current or future U.S. Treasury Regulations or rulings promulgated thereunder, any intergovernmental agreement between the United States and any other jurisdiction to implement FATCA (an “IGA”), any law, regulation or other official guidance enacted in any jurisdiction implementing FATCA or an IGA, or any agreement with the U.S. Internal Revenue Service under or with respect to FATCA; or
(x) any combination of the taxes referred to in (i) through (ix) above.
In addition, no payments of additional amounts will be made with respect to any payment on a note if the holder of the note is a fiduciary, partnership or a person other than the sole beneficial owner of any payment that would be required, by the laws of the jurisdiction in which we are resident for tax purposes, to be included in income, for tax purposes, of a beneficiary or settlor with respect to the fiduciary, a member of that partnership or a beneficial owner who would not have been entitled to the additional amounts had that beneficiary, settlor, partner or beneficial owner been the holder of the relevant notes.
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Defeasance and Discharge
We may release ourselves from any payment or other obligations on each series of notes as described under “Description of Debt Securities — Satisfaction, Discharge and Defeasance” in the attached prospectus.
Paying and Calculation Agent
The principal corporate trust office of the trustee in The City of New York is designated as the principal paying agent. See “— Trustee” immediately below. We may at any time designate additional paying agents or rescind the designation of paying agents or approve a change in the office through which any paying agent acts. The trustee will also serve as the calculation agent with respect to the Floating Rate Notes pursuant to a Calculation Agency Agreement to be dated as of November , 2015 between us and The Bank of New York Mellon.
Trustee
As a result of the transfer of JPMorgan Chase Bank’s corporate trust business to The Bank of New York Mellon (formerly known as The Bank of New York), effective October 1, 2006, The Bank of New York Mellon is currently the trustee under the Indenture. The trustee’s current address is The Bank of New York Mellon, Corporate Trust Office, 101 Barclay Street, New York, NY 10286. The trustee will also serve as the paying agent for the notes and as the calculation agent with respect to the Floating Rate Notes. See “— Paying and Calculation Agent” immediately above.
See “Description of Debt Securities — Concerning the Trustee” and “Description of Debt Securities — Default and Related Matters” in the attached prospectus for a description of the trustee’s procedures and remedies available in the event of default.
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Taxation
The following supplements the discussion under “Certain UK and US Federal Tax Considerations” in the attached prospectus and is subject to the limitations and exceptions set forth therein.
European Union Savings Income Directive
On March 24, 2014, the Council of the European Union adopted a Council Directive (the “Amending Directive”) amending and broadening the scope of the requirements described under “Certain UK and US Federal Tax Considerations — United Kingdom Taxation — European Union Savings Income Directive” of the attached prospectus. Member States are required to apply these new requirements from January 1, 2017. The changes would expand the range of payments covered by Council Directive 2003/48/EC on the taxation of savings income (the “Savings Directive”), in particular to include additional types of income payable on securities. The Amending Directive would also apply a “look through approach” to payments made via certain persons, entities or legal arrangements (including trusts and partnerships), where certain conditions are satisfied, where an individual resident in a Member State is regarded as the beneficial owner of the payment for the purposes of the Amending Directive. This approach may in some cases apply where the person, entity or arrangement is established or effectively managed outside of the European Union.
Luxembourg, which before January 1, 2015 operated a withholding tax under the transitional rules described in the attached prospectus, has now replaced such withholding tax with the information reporting regime described in the attached prospectus.
The European Commission has proposed the repeal of the Savings Directive from January 1, 2017 in the case of Austria and from January 1, 2016 in the case of all other Member States (subject to on-going requirements to fulfil administrative obligations such as the reporting and exchange of information relating to, and accounting for withholding taxes on, payments made before those dates). This is to prevent overlap between the Savings Directive and a new automatic exchange of information regime to be implemented under Council Directive 2011/16/EU on Administrative Cooperation in the field of Taxation (as amended by Council Directive 2014/107/EU). The proposal also provides that, if it proceeds, Member States will not be required to apply the new requirements of the Amending Directive.
The proposed financial transaction tax (“FTT”)
On February 14, 2013, the European Commission published a proposal (the “Commission’s Proposal”) for a Directive for a common FTT in Belgium, Germany, Estonia, Greece, Spain, France, Italy, Austria, Portugal, Slovenia and Slovakia (the “participating Member States”). Joint statements issued by participating Member States indicate an intention to implement the FTT by January 1, 2016.
The Commission’s
Proposal has very broad scope and the FTT could, if introduced, apply to certain dealings in the debt securities (including secondary
market transactions) in certain circumstances, and to persons both within and outside of the participating Member States. However,
the FTT proposal remains subject to negotiation between the participating Member States and the scope and timing of any such tax
is uncertain.
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Clearance and Settlement
The notes will be issued in the form of global notes that will be deposited with DTC on the closing date. This means that we will not issue certificates to each holder. We will issue one or more global notes with respect to each series of notes to DTC, and DTC will keep a computerized record of its participants (for example, your broker) whose clients have purchased the notes. The participant will then keep a record of its clients who purchased the notes. Unless it is exchanged in whole or in part for a certificated note, a global note may not be transferred; except that DTC, its nominees, and their successors may transfer a global note as a whole to one another. We will not issue certificated notes except in limited circumstances that we explain under “Legal Ownership — Global Securities — Special situations when the global security will be terminated” in the attached prospectus.
Beneficial interests in the global notes will be shown on, and transfers of the global notes will be made only through, records maintained by DTC and its participants. A description of DTC and its procedures is set forth under “Clearance and Settlement” in the attached prospectus.
We will wire principal and interest payments to DTC’s nominee. We and the trustee will treat DTC’s nominee as the owner of the global notes for all purposes. Accordingly, we, the trustee and any paying agent will have no direct responsibility for liability to pay amounts due on the global notes to owners of beneficial interests in the global note.
It is DTC’s current practice, upon receipt of any payment of principal or interest, to credit direct participants’ accounts on the payment date according to their respective holdings of beneficial interest in the global note as shown on DTC’s records. In addition, it is DTC’s current practice to assign any consenting or voting right to direct participants whose accounts are credited with notes on a record date, by using an omnibus proxy. Payments by participants to owners of beneficial interest in the global note, and voting by participants, will be governed by the customary practices between the participants and owners of beneficial interest, as is the case with notes held for the account of customers registered in “street name”. However, payments will be the responsibility of the participants and not of DTC, the trustee or us.
Settlement for the notes will be made by the underwriters in immediately available funds. All payments of principal and interest will be made in immediately available funds, except as otherwise indicated in this section.
The notes have been accepted for clearance through DTC, Clearstream, Luxembourg and Euroclear. For the 2018 Notes, the ISIN is and the CUSIP number is . For the 2020 Notes, the ISIN is and the CUSIP number is .. For the 2025 Notes, the ISIN is and the CUSIP number is . For the 2045 Notes, the ISIN is and the CUSIP number is . For the Floating Rate Notes, the ISIN is and the CUSIP number is ..
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Underwriting
Subject to the terms and conditions set forth in the underwriting agreement dated November , 2015, and incorporated in the pricing agreement dated November , 2015, each of the underwriters has severally agreed to purchase, and we have agreed to sell to each underwriter, the principal amount of notes set forth opposite the name of each underwriter.
Underwriter | 2018 Notes Principal Amount | 2020 Notes Principal Amount | 2025 Notes Principal Amount | 2045 Notes Principal Amount | Floating Rate Notes Principal Amount | |||||
Barclays Capital Inc. | $ | $ | $ | $ | $ | |||||
HSBC Securities (USA) Inc. | ||||||||||
Merrill Lynch, Pierce, Fenner & Smith Incorporated | ||||||||||
Morgan Stanley & Co. LLC | ||||||||||
Total | $ | $ | $ | $ |
Barclays Capital Inc., Morgan Stanley & Co. LLC, HSBC Securities (USA) Inc. and Merrill Lynch, Pierce, Fenner & Smith Incorporated are the joint book-running managers for this offering of notes and are acting as representatives of the underwriters.
The underwriting agreement and the pricing agreement provide that the obligations of the several underwriters are subject to certain conditions. The underwriters are obligated to purchase all of the notes if they purchase any of the notes.
The underwriters will initially offer to sell the notes to the public at the initial public offering price set forth on the cover of this prospectus supplement. The underwriters may sell notes to securities dealers at a discount from the initial public offering price of up to % of the principal amount of the 2018 Notes, % of the principal amount of the 2020 Notes, % of the principal amount of the 2025 Notes, % of the principal amount of the 2045 Notes and % of the principal amount of the Floating Rate Notes. These securities dealers may resell any notes purchased from the underwriters to other brokers or dealers at a discount from the initial public offering price of up to % of the principal amount of the 2018 Notes, % of the principal amount of the 2020 Notes, % of the principal amount of the 2025 Notes, % of the principal amount of the 2045 Notes and % of the principal amount of the Floating Rate Notes. If the underwriters cannot sell all the notes at the initial offering price, they may change the offering price and the other selling terms.
The notes are a new issue of securities with no established trading market. We will apply to list the notes on the New York Stock Exchange. The underwriters have advised us that they intend to make a market in the notes, but are not obligated to do so and may discontinue market making at any time without notice. Therefore, no assurance can be given as to the liquidity of the trading market for the notes.
The following table shows the underwriting discounts and commissions that we are to pay to the underwriters in connection with this offering (expressed as a percentage of the principal amount of the notes).
Paid by Us | |
Per 2018 Note | % |
Per 2020 Note | % |
Per 2025 Note | % |
Per 2045 Note | % |
Per Floating Rate Note | % |
In connection with the offering, the underwriters may purchase and sell notes in the open market. These transactions may include over-allotment, syndicate covering transactions and stabilizing transactions. Over-allotment involves syndicate sales of notes in excess of the principal amount of notes to be purchased by the underwriters in the offering, which creates a syndicate short position. Syndicate covering transactions involve purchases of the notes in the open market after the distribution has been completed in order to cover syndicate short
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positions. Stabilizing transactions consist of certain bids or purchases of notes made for the purpose of preventing or retarding a decline in the market price of the notes while the offering is in progress.
The underwriters also may impose a penalty bid. Penalty bids permit the underwriters to reclaim a selling concession from a syndicate member when the underwriters, in covering syndicate short positions or making stabilizing purchases, repurchase notes originally sold by that syndicate member.
Any of these activities may have the effect of stabilizing, preventing or retarding a decline in the market price of the notes. They may also cause the price of the notes to be higher than the price that otherwise would exist in the open market in the absence of these transactions. The underwriters may conduct these transactions in the over-the-counter market or otherwise. If the underwriters commence any of these transactions, they may discontinue them at any time.
The offering of the notes by the underwriters is subject to receipt and acceptance and subject to the underwriters’ right to reject any order in whole or in part.
We estimate that expenses, excluding underwriting discounts and commissions, will be approximately $ .
We have agreed to indemnify the several underwriters against various liabilities, including liabilities under the Securities Act of 1933, or to contribute to payments the underwriters may be required to make in respect of any of those liabilities.
The underwriters and their respective affiliates are full service financial institutions engaged in various activities, which may include sales and trading, commercial and investment banking, advisory, investment management, investment research, principal investment, hedging, market making, brokerage and other financial and non-financial activities and services. Certain of the underwriters and their respective affiliates have provided, and may in the future provide, a variety of these services to us and to persons and entities with relationships with us, for which they received or will receive customary fees and expenses. Certain of the underwriters are lenders under our revolving credit facility.
In the ordinary course of their various business activities, the underwriters and their respective affiliates, officers, directors and employees may purchase, sell or hold a broad array of investments, including serving as counterparties to certain derivative and hedging arrangements, and actively trade securities, derivatives, loans, commodities, currencies, credit default swaps and other financial instruments for their own account and for the accounts of their customers, and such investment and trading activities may involve or relate to our assets, securities and/or instruments (directly, as collateral securing other obligations or otherwise) and/or persons and entities with relationships with us. Certain of the underwriters or their affiliates that have a lending relationship with us routinely hedge their credit exposure to us consistent with their customary risk management policies. Typically, such underwriters and their affiliates would hedge such exposure by entering into transactions which consist of either the purchase of credit default swaps or the creation of short positions in our securities, including potentially the notes offered hereby. Any such credit default swaps or short positions could adversely affect future trading prices of the notes offered hereby. The underwriters and their respective affiliates may also communicate independent investment recommendations, market color or trading ideas and/or publish or express independent research views in respect of such assets, securities or instruments and may at any time hold, or recommend to clients that they should acquire, long and/or short positions in such assets, securities and instruments.
It is expected that delivery of the notes will be made against payment therefore on or about the date specified in the last paragraph of the cover page of this prospectus supplement, which will be the third day following the date of pricing of the notes (such settlement cycle being herein referred to as “T+3”).
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Selling Restrictions
European Economic Area
In relation to each Member State of the European Economic Area which has implemented the Prospectus Directive (each, a “Relevant Member State”), with effect from and including the date on which the Prospectus Directive is implemented in that Relevant Member State (the “Relevant Implementation Date”) an offer of the notes may not be made to the public in that Relevant Member State other than:
(a) | to any legal entity which is a qualified investor as defined in the Prospectus Directive; |
(b) | to fewer than 150 natural or legal persons (other than qualified investors as defined in the Prospectus Directive), subject to obtaining the prior consent of the representatives of the several underwriters; or |
(c) | in any other circumstances falling within Article 3(2) of the Prospectus Directive, |
provided that no such offer of notes shall require us or any underwriter to publish a prospectus pursuant to Article 3 of the Prospectus Directive.
For the purposes of this provision, the expression an “offer of notes to the public” in relation to any notes in any Relevant Member State means the communication in any form and by any means of sufficient information on the terms of the offer and the notes to be offered so as to enable an investor to decide to purchase or subscribe the notes, as the same may be varied in that Member State by any measure implementing the Prospectus Directive in that Member State and the expression “Prospectus Directive” means Directive 2003/71/EC (as amended including by Directive 2010/73/EU and including any relevant implementing measure in each Relevant Member State).
United Kingdom
Each underwriter has represented and agreed that, in connection with the distribution of the notes:
(a) | it has complied and will comply with all applicable provisions of the Financial Services and Markets Act 2000 (“FSMA”) with respect to anything done by it in relation to the notes in, from or otherwise involving the United Kingdom; and |
(b) | it has only communicated or caused to be communicated and will only communicate or cause to be communicated an invitation or inducement to engage in investment activity (within the meaning of Section 21 of the FSMA) received by it in connection with the issue and sale of such notes in circumstances in which Section 21(1) of the FSMA does not apply to us. |
This document has not been approved by an authorised person for the purposes of section 21 of the FSMA. Accordingly, this document is only for distribution to and directed at: (i) persons outside the United Kingdom; or (ii) investment professionals falling within Article 19(5) of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2005, as amended, (the “Order”); or (iii) high net worth entities, and other persons to whom it may lawfully be communicated, falling within Article 49(2)(a) to (d) of the Order (all such persons together being referred to as “Relevant Persons”). Any investment or investment activity to which this document relates is available only to and will be engaged in only with Relevant Persons. Persons who are not Relevant Persons should not take any action based upon this document and should not rely on it.
Canada
The notes may be sold in Canada only to purchasers purchasing, or deemed to be purchasing, as principal that are accredited investors, as defined in National Instrument 45-106 Prospectus Exemptions or subsection 73.3(1) of the Securities Act (Ontario), and are permitted clients, as defined in National Instrument 31-103 Registration Requirements, Exemptions and Ongoing Registrant Obligations. Any resale of the notes must be made in accordance with an exemption from, or in a transaction not subject to, the prospectus requirements of applicable securities laws.
Securities legislation in certain provinces or territories of Canada may provide a purchaser with remedies for rescission or damages if this document (including any amendment thereto) contains a misrepresentation, provided
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that the remedies for rescission or damages are exercised by the purchaser within the time limit prescribed by the securities legislation of the purchaser’s province or territory. The purchaser should refer to any applicable provisions of the securities legislation of the purchaser’s province or territory for particulars of these rights or consult with a legal advisor.
Pursuant to section 3A.3 of National Instrument 33-105 Underwriting Conflicts (NI 33-105), the underwriters are not required to comply with the disclosure requirements of NI 33-105 regarding underwriter conflicts of interest in connection with this offering.
Hong Kong
The notes may not be offered or sold by means of any document other than (i) in circumstances which do not constitute an offer to the public within the meaning of the Companies Ordinance (Cap.32, Laws of Hong Kong), or (ii) to "professional investors" within the meaning of the Securities and Futures Ordinance (Cap.571, Laws of Hong Kong) and any rules made thereunder, or (iii) in other circumstances which do not result in the document being a "prospectus" within the meaning of the Companies Ordinance (Cap.32, Laws of Hong Kong), and no advertisement, invitation or document relating to the notes may be issued or may be in the possession of any person for the purpose of issue (in each case whether in Hong Kong or elsewhere), which is directed at, or the contents of which are likely to be accessed or read by, the public in Hong Kong (except if permitted to do so under the laws of Hong Kong) other than with respect to notes which are or are intended to be disposed of only to persons outside Hong Kong or only to “professional investors” within the meaning of the Securities and Futures Ordinance (Cap. 571, Laws of Hong Kong) and any rules made thereunder.
Singapore
This prospectus supplement has not been registered as a prospectus with the Monetary Authority of Singapore. Accordingly, this prospectus supplement and any other document or material in connection with the offer or sale, or invitation for subscription or purchase, of the notes may not be circulated or distributed, nor may the notes be offered or sold, or be made the subject of an invitation for subscription or purchase, whether directly or indirectly, to persons in Singapore other than (i) to an institutional investor under Section 274 of the Securities and Futures Act, Chapter 289 of Singapore (the “SFA”), (ii) to a relevant person, or any person pursuant to Section 275(1A), and in accordance with the conditions, specified in Section 275 of the SFA or (iii) otherwise pursuant to, and in accordance with the conditions of, any other applicable provision of the SFA.
Where the notes are subscribed or purchased under Section 275 by a relevant person which is: (a) a corporation (which is not an accredited investor) the sole business of which is to hold investments and the entire share capital of which is owned by one or more individuals, each of whom is an accredited investor; or (b) a trust (where the trustee is not an accredited investor) whose sole purpose is to hold investments and each beneficiary is an accredited investor, shares, debentures and units of shares and debentures of that corporation or the beneficiaries' rights and interest in that trust shall not be transferable for 6 months after that corporation or that trust has acquired the notes under Section 275 except: (1) to an institutional investor under Section 274 of the SFA or to a relevant person, or any person pursuant to Section 275(1A), and in accordance with the conditions, specified in Section 275 of the SFA; (2) where no consideration is given for the transfer; or (3) by operation of law.
Japan
The notes have not been and will not be registered under the Financial Instruments and Exchange Law of Japan (the Financial Instruments and Exchange Law) and each underwriter has agreed that it will not offer or sell any notes, directly or indirectly, in Japan or to, or for the benefit of, any resident of Japan (which term as used herein means any person resident in Japan, including any corporation or other entity organized under the laws of Japan), or to others for re-offering or resale, directly or indirectly, in Japan or to a resident of Japan, except pursuant to an exemption from the registration requirements of, and otherwise in compliance with, the Financial Instruments and Exchange Law and any other applicable laws, regulations and ministerial guidelines of Japan.
Validity of Notes
Davis Polk & Wardwell London LLP, our US counsel, and Sullivan & Cromwell LLP, US counsel for the underwriters, will pass upon the validity of the notes with respect to United States Federal
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law and New York State law. Freshfields Bruckhaus Deringer LLP, our English solicitors, will pass upon the validity of the notes with respect to English law.
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About This Prospectus
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Astrazeneca PLC
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Risk Factors
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Forward-Looking Statements
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Enforceability of Certain Civil Liabilities
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Where You Can Find More Information About Us
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Incorporation of Documents by Reference
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Use of Proceeds
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Legal Ownership
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Description of Debt Securities
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Clearance and Settlement
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Certain UK and US Federal Tax Considerations
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Plan of Distribution
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Legal Matters
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Experts
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the loss or expiration of patents;
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marketing exclusivity or trademarks;
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the risk of substantial adverse litigation/government investigation claims and insufficient insurance coverage;
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exchange rate fluctuations;
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the risk that R&D will not yield new products that achieve commercial success;
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the risk that strategic alliances will be unsuccessful;
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the impact of competition, price controls and price reductions;
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taxation risks;
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the risk of substantial product liability claims;
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the impact of any failure by third parties to supply materials or services;
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the risk of failure to manage a crisis;
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the risk of delay to new product launches;
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the difficulties of obtaining and maintaining regulatory approvals for products;
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the risk of failure to observe ongoing regulatory oversight;
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the risk that new products do not perform as we expect;
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the risk of environmental liabilities;
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the risk associated with conducting business in emerging markets;
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the risk of reputational damage;
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the risk of product counterfeiting; and
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other factors discussed under “Risk Factors” and elsewhere in this document.
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Our Report on Form 6-K/A furnished to the SEC on October 31, 2013.
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Our Report on Form 6-K furnished to the SEC on October 31, 2013, which includes our interim consolidated results for the nine-month period ended September 30, 2013.
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Our Annual Report on Form 20-F for the year ended December 31, 2012 filed with the SEC on March 25, 2013.
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All other documents we file pursuant to Section 13(a), 13(c) or 15(d) of the Securities Exchange Act of 1934, as amended, after the date of this prospectus and prior to the termination of the offering of the securities and, to the extent designated therein, reports furnished to the SEC on Form 6-K, in each case with effect from the date that such document or report is so filed or furnished.
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AstraZeneca PLC
The Company Secretary
2 Kingdom Street
London W2 6BD
England
Tel. No.: +44-20-7604-8000
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AstraZeneca PLC
Investor Relations
2 Kingdom Street
London W2 6BD
England
Tel. No.: +44-20-7604-8000
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how it handles securities payments and notices;
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whether it imposes fees or charges;
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how it would handle voting if it were ever required;
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whether and how you can instruct it to send you securities registered in your own name so you can be a direct holder as described below; and
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how it would pursue rights under the securities if there were a default or other event triggering the need for holders to act to protect their interests.
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you cannot have securities registered in your own name;
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you cannot receive physical certificates for your interest in the securities;
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you will be a street name holder and must look to your own bank or broker for payments on the securities and protection of your legal rights relating to the securities, as explained earlier under “— Street Name and Other Indirect Holders”;
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you may not be able to sell interests in the securities to some insurance companies and other institutions required by law to own securities in the form of physical certificates;
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the depositary’s policies will govern payments, transfers, exchange and other matters relating to your interest in the global security. We and the trustee have no responsibility for any aspect of the depositary’s actions or for its records of ownership interests in the global security. We and the trustee also do not supervise the depositary in any way; and
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the depositary will require that interests in a global security be purchased or sold within its system using same-day funds.
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the depositary notifies us that it is unwilling or unable to continue as depositary, or if the depositary is no longer qualified as a clearing agency under applicable law and we have not appointed a successor depositary;
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we decide at any time and in our sole discretion not to have any of the securities represented by registered securities in global form;
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an event of default on the securities has occurred and has not been cured; or
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any other circumstances for terminating a global security as described in the applicable prospectus supplement have occurred.
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In this description “you” means direct holders and not street name or other indirect holders of securities. Indirect holders should read the section “Legal Ownership — Street Names and Other Indirect Holders” above.
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first, it can enforce your rights against us if we default on debt securities issued under the indenture. There are some limitations on the extent to which the trustee may act on your behalf, described under “Defaults and Related Matters — Remedies if an event of default occurs” below; and
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second, the trustee performs administrative duties for us, such as sending you interest payments and notices.
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the title of the series of debt securities;
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the aggregate principal amount of debt securities and any limit on the aggregate principal amount of the series of debt securities;
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any stock exchange on which we will list the debt securities;
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the date or dates on which we will repay the principal amount of the series of debt securities or the method by which the date or dates will be determined;
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any rate or rates at which the series of debt securities will bear interest or the method by which the interest rate or rates will be determined;
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the date or dates from which any interest on the series of debt securities will accrue, the dates on which interest will be payable and the record dates for interest payments or the method by which such date or dates will be determined and the method by which interest will be calculated if different to a 360-day year of twelve 30-day months;
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the place or places where the principal and any interest on debt securities will be payable if other than the corporate trust office of the trustee in New York, New York;
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the price or prices at which, the period or periods within which, the currency or currencies, currency unit or composite currency in which, and the terms and conditions upon which we may redeem the series of debt securities in whole or in part;
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any right or obligation to redeem, repay or purchase the debt securities as a result of any sinking fund or similar provisions, or at the option of the holder of the debt securities and the period or periods within which, the price or prices at which and every other term and condition upon which the debt securities will be redeemed, repaid or purchased;
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the denominations in which debt securities of the series are issuable, if other than denominations of $2,000 and any whole multiple of $1,000 in excess thereof;
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the portion of the principal amount of the series of debt securities payable if an acceleration of the maturity of the debt securities is declared, if other than the principal amount;
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the currency, including any composite currency, of payment of the principal, premium, if any, and interest on the series of debt securities if other than US dollars;
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whether we or a holder of debt securities may elect to have the principal, premium, if any, or interest on the series of debt securities paid in a currency or composite currency other than the currency in which the debt securities are stated to be payable, and if so, any election period and the terms and conditions governing such an election;
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whether we will be required to pay additional amounts for withholding taxes or other governmental charges and, if applicable, a related right to an optional tax redemption for such a series;
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any index used to determine the amount of payment of principal, premium, if any, and interest on the series of debt securities and how these amounts will be determined if they are not fixed when the debt securities are issued;
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the forms of the series of debt securities;
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the applicability of the provisions described later under “— Satisfaction, Discharge and Defeasance”;
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any authenticating or paying agents, transfer agents or registrars or any other agents acting in connection with the debt securities other than the trustee;
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if applicable, a discussion of any additional material US federal income and UK tax considerations; and
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any other special features of the series of debt securities.
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Additional mechanics relevant to the debt securities under normal circumstances, such as how you transfer ownership and where we make payments.
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Your right to receive payment of additional amounts due to changes in the tax withholding requirements of various jurisdictions.
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Your rights under several special situations, such as if we merge with another company or if we want to redeem the debt securities for tax reasons.
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Covenants contained in the indenture that restrict our ability to incur liens and undertake sale and leaseback transactions. A particular series of debt securities may have different covenants.
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Your rights if we default.
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Your rights if we want to modify the indenture.
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Our relationship with the trustee.
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the tax, levy, impost or other governmental charge would not have been imposed, assessed, levied or collected but for the holder’s (or certain related parties’) connection to the jurisdiction in which we are resident for tax purposes, other than by merely holding the debt security or by receiving principal, premium, if any, or interest, if any, on the debt security, or enforcing the debt security. These connections include where the holder or related party:
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is or has been a domiciliary, national or resident of such jurisdiction;
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is or has been engaged in a trade or business in such jurisdiction;
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has or had a permanent establishment in such jurisdiction; or
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is or has been physically present in such jurisdiction.
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the tax, levy, impost or other governmental charge would not have been imposed, assessed, levied or collected but for presentation of the debt security for payment, if presentation is required, more than 30 days after the security became due or payment was provided for;
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the tax, levy, impost or other governmental charge is an estate, inheritance, gift, sale, transfer, personal property or similar tax, levy, impost or other governmental charge;
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the tax, levy, impost or other governmental charge is payable in a manner that does not involve deduction or withholding from payments on or in respect of the relevant debt security;
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the tax, levy, impost or other governmental charge would not have been imposed or withheld but for the failure of the holder or beneficial owner to comply with any certification, identification or other reporting requirement concerning the nationality, residence, identity or connection with any jurisdiction in which we are resident for tax purposes, as required by any treaty, statute, regulation or administrative practice of such jurisdiction as a condition to relief or exemption from such tax, levy, impost or other governmental charge;
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the tax, levy, impost or other governmental charge is imposed on a payment to or for an individual and is required to be made pursuant to the European Union Directive 2003/48/EC on the taxation of savings or any other directive implementing the conclusions of the ECOFIN Council meeting of 26-27 November 2000 or any law implementing or complying with, or introduced in order to conform to, such Directive;
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the holder would have been able to avoid such withholding or deduction by authorizing the paying agent to report information in accordance with the procedure laid down by the relevant tax authority or by producing, in the form required by the relevant tax authority, a declarative, claim, certificate, document or other evidence establishing exemption therefrom;
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the tax, levy, impost or other governmental charge is imposed by the United States or any political subdivision or taxing authority thereof or therein;
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the holder would have been able to avoid such withholding or deduction by presenting the relevant debt security to another paying agent in a Member State of the EU or elsewhere;
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the holder of the debt security is a fiduciary, partnership or a person other than the sole beneficial owner of any payment that would be required, by the laws of the jurisdiction in which we are resident for tax purposes, to be included in income, for tax purposes, of a beneficiary or settlor with respect to the fiduciary, a member of that partnership or a beneficial owner who would not have been entitled to the additional amounts had that beneficiary, settlor, partner or beneficial owner been the holder; or
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any combination of the exceptions listed above. (Section 3.02)
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any entity succeeding us must assume our obligations in relation to the debt securities and under the indenture;
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if the succeeding entity is not organized under the laws of the United Kingdom or a State of the United States, the succeeding entity’s assumption of our obligations in relation to the debt securities and under the indenture must include the obligation to pay any additional amounts as described under “— Payment of Additional Amounts”. (Section 8.01)
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Restricted subsidiary means any wholly-owned subsidiary:
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with substantially all of its property located within the UK or the US; and
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which owns a principal property;
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A wholly-owned subsidiary means any corporation in which control, directly or indirectly, of all of the stock with ordinary voting power to elect the board of directors of that corporation is owned by us, or by one or more of our wholly-owned subsidiaries or by us and one or more of our wholly-owned subsidiaries.
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A subsidiary, with respect to any person, is any corporation in which that person owns or controls directly or indirectly at least a majority of stock with ordinary voting power to elect a majority of the board of directors.
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Principal property means any manufacturing plant or facility or any research facility owned by us or any restricted subsidiary. A principal property must also be located within the UK or the US and have a gross book value (before deducting any depreciation reserve) exceeding 2% of our consolidated net tangible assets. Principal property does not include:
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any plant or facility or research facility which in the opinion of our board of directors is not materially important to the total business conducted by us and our subsidiaries; or
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any portion of a property described above which, in the opinion of our board of directors, is not materially important to the use or operation of the property. (Section 1.01)
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Our consolidated net tangible assets mean AstraZeneca PLC’s consolidated total assets, after deducting:
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all liabilities due within one year (other than short-term borrowings and long-term debt due within one year); and
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all goodwill, trade names, trademarks, patents and other similar types of intangible assets as shown on the audited consolidated balance sheet contained in the latest annual report to our shareholders. (Section 1.01)
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any lien on property, shares of stock or indebtedness of any corporation existing at the time the corporation becomes a restricted subsidiary;
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any lien on property or shares of stock existing at the time of acquisition of that property or those shares of stock, or to secure the payment of all or any part of the purchase price of that property or those shares of stock, or to secure any debt incurred before, at the time of, or within twelve months after, in the case of shares of stock, the acquisition of the shares of stock and, in the case of property, the later of the acquisition, completion of construction (including any improvements on an existing property) or commencement of the commercial operation of the property, where the debt is incurred to finance all or any part of the purchase price;
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any lien securing debt owed to us or to any of our restricted subsidiaries by us or any of our restricted subsidiaries;
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any lien existing at the date of the indenture;
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any lien on a principal property to secure debt incurred to finance all or part of the cost of improving, constructing, altering or repairing any building, equipment or facilities or of any other improvements on all or any part of that principal property, if the debt is incurred before, during, or within twelve months after completing the improvement, construction, alteration or repair;
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any lien on property owned or held by any corporation or on shares of stock or indebtedness of any corporation, where the lien existed either at the time the corporation is merged, consolidated or
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amalgamated with either us or a restricted subsidiary or at the time of a sale, lease or other disposition of all or substantially all of the property of a corporation to us or a restricted subsidiary;
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any lien arising by operation of law and not securing amounts more than 90 days overdue or otherwise being contested in good faith;
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any lien arising by operation of law over any credit balance or cash held in any account with a financial institution;
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any rights of financial institutions to offset credit balances in connection with the operation of cash management programs established for our benefit and/or the benefit of any restricted subsidiary;
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any lien incurred or deposits made in the ordinary course of business, including but not limited to:
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any mechanics’, materialmen’s, carriers’, workmen’s, vendors’ or other similar liens;
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any liens securing amounts in connection with workers’ compensation, unemployment insurance and other types of social security; and
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any easements, rights-of-way, restrictions and other similar charges;
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any liens incurred or deposits made securing the performance of tenders, bids, leases, statutory obligations, surety and appeal bonds, government contracts, performance and return of money bonds and other obligations of a similar nature incurred in the ordinary course of business;
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any lien securing taxes or assessments or other applicable governmental charges or levies;
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any extension, renewal or replacement or successive extensions, renewals or replacements, in whole or in part, of any lien included in the preceding paragraphs or of any of the debt secured under the preceding paragraphs, so long as the principal amount of debt secured does not exceed the principal amount of debt secured at the time of the extension, renewal or replacement, and that the extension, renewal or replacement lien is limited to all or any part of the same property or shares of stock that secured the lien extended, renewed or replaced (including improvements on that property), or property received or shares of stock issued in substitution or exchange; and
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any lien in favor of us or any subsidiary of ours.
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any liens on property of ours or a restricted subsidiary in favor of the US or any State of the US, or the UK, or any other country, or any political subdivision of, or any department, agency or instrumentality of, these countries or states, to secure partial, progress, advance or other payments under provisions of any contract or statute including, but not limited to, liens to secure debt of pollution control or industrial revenue bond type, or to secure any indebtedness incurred for the purpose of financing all or any part of the purchase price or cost of construction of the property subject to these liens. (Section 3.09)
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we or the restricted subsidiary seeking to enter into the sale and lease-back could incur, assume or guarantee debt secured by a lien on the principal property to be leased without equally and ratably securing the debt securities offered by this prospectus as a result of one or more of the exceptions to the limitation on liens as described under “— Limitation on Liens” above;
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within twelve months before or after the sale or transfer, regardless of whether the sale or transfer may have been made by us or a restricted subsidiary, we apply, an amount equal to the net proceeds of the sale or transfer (in the case of a sale or transfer for cash), or an amount equal to the fair value of the principal property so leased at the time of entering into the sale or transfer as determined by our board of directors (in the case of a sale or transfer otherwise than for cash), to
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the retirement of indebtedness for money borrowed, incurred or assumed by us or any restricted subsidiary which matures at, or is extendible or renewable at the option of the obligor to, a date more than twelve months after the date of incurring, assuming or guaranteeing such debt, or
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investment in any principal property or principal properties. (Section 3.09)
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Interest — default for 30 days in the payment of any installment of interest on the series of debt securities;
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Principal — default in the payment of all or any part of the principal of the series of debt securities when such principal becomes due and payable either at maturity, upon redemption, by acceleration or otherwise;
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Sinking Fund Installment — default in the payment of any sinking fund installment as and when such installment becomes due and payable by the specific terms of the series of debt securities or beyond any period of grace;
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Covenant — breach or default by us in the performance of a covenant or warranty in respect of the debt securities of the relevant series which has not been remedied for ninety days after we receive written notice of the default from the trustee or we and the trustee receive written notice of the default from the holders of at least 25% of the principal amount of the debt securities of all affected series;
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Bankruptcy — certain events of bankruptcy, insolvency or reorganization affecting us; or
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Other — any other event of default provided in any supplemental indenture or resolution of our board of directors under which a particular series is issued or in the form of security for such series.
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you must give the trustee written notice that an event of default has occurred and remains uncured;
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the holders of 25% in principal amount of all outstanding debt securities of the relevant series must make a written request that the trustee take action because of the default, and must offer reasonable indemnity to the trustee against the cost and other liabilities of taking that action; and
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the trustee must have not taken action for 60 days after receipt of the above notice and offer of indemnity and the trustee has not received an inconsistent direction from the holders of a majority in principal amount of all outstanding debt securities of the relevant series during that period. (Section 4.06)
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to transfer or pledge any property or assets to the trustee as security for any series of the debt securities;
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to evidence the succession of any successor corporation to us as described under “Mergers and Similar Events” above;
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to evidence the succession of any successor trustee under the indenture or to add to or change any provisions of the indenture as necessary to provide for the appointment of an additional trustee or trustees;
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to add to our covenants or to add additional events of default for the benefit of the holders of any series of the debt securities;
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to cure any ambiguity or to correct or supplement any provision of the indenture that may be defective or inconsistent with any other provision of the indenture; or
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to make any other provisions with respect to matters or questions arising under the indenture as our board of directors may deem necessary or desirable and that shall not adversely affect the interests of holders of any series of the debt securities in any material respect. (Section 7.01)
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extend the final maturity of a debt security;
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reduce the principal amount of a debt security;
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reduce the rate or extend the time of payment of any interest on a debt security;
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reduce any amount payable on redemption of a debt security;
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reduce the amount of principal due and payable upon an acceleration of the maturity or provable in bankruptcy of a debt security issued at an original issue discount;
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impair your right to sue for payment;
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impair any right of repayment at the option of the holder;
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reduce the percentage of holders of debt securities whose consent is needed to modify or amend the indenture; or
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change in any manner adverse to the holders of the debt securities our obligations relating to the payment of principal and interest, and sinking fund payments. (Section 7.02)
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we have paid or caused to be paid the principal of and interest, if any, then due and payable on all outstanding debt securities of any series; or
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we have delivered to the trustee for cancellation all outstanding debt securities of any series; or
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all the outstanding debt securities of the series that have not been delivered to the trustee for cancellation have become or will become due and payable within one year and we have made arrangements satisfactory to the trustee for the giving of notice of redemption by the trustee in our name; and
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we have deposited with the trustee sufficient funds to pay and discharge the entire indebtedness on the series of debt securities to pay principal and interest, if any, and paid all other sums payable under the indenture. (Section 9.01)
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we must deposit in trust for your benefit and the benefit of all other direct holders of the debt securities a combination of money and government obligations that will generate enough cash to make interest, principal and any other payments on the debt securities on their various due dates; and
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we must deliver to the trustee a legal opinion of our counsel to the effect that the holders of the debt securities of that series will not recognize gain or loss for US federal income tax purposes as a result of the defeasance and will be subject to the same federal income tax as would be the case if the defeasance did not occur. (Section 9.03)
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to register the transfer and exchange of debt securities and our right of optional redemption, if any;
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to replace mutilated, defaced, destroyed, lost or stolen debt securities;
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to pay principal and interest, if any, on the original stated due dates and any remaining rights of the holders to receive sinking fund payments, if any, from funds deposited with the trustee;
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immunities of the trustee; and
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to hold money for payment in trust. (Section 9.01)
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direct obligations of the US or any foreign government of a sovereign state for the payment of which is pledged by the full faith and credit of the US or such foreign government; or
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obligations of an entity controlled or supervised by and acting as an agency or instrumentality of the US or any foreign government of a sovereign state the payment of which is unconditionally guaranteed as a full faith and credit obligation of the US or such foreign government;
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a depositary receipt issued by a bank or trust company as custodian for these government obligations, or specific payment of interest on or principal of these government obligations, held by such custodian for the account of the holder of a depositary receipt, provided that (except as required by law) such custodian is not authorized to make any deductions from the amount payable to the holder of such depositary receipt from any amount received by the custodian in respect of these government obligations, or the specific payment of interest on or principal of these government obligations, evidenced by such depositary receipt. (Section 1.01)
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DTC is a limited-purpose trust company organized under the laws of the State of New York, a “banking organization” within the meaning of the New York Banking Law, a member of the Federal Reserve System, a “clearing corporation” within the meaning of the New York Uniform Commercial Code, and a “clearing agency” registered pursuant to the provisions of Section 17A of the Securities Exchange Act of 1934.
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DTC was created to hold securities for its participants and to facilitate the clearance and settlement of securities transactions, such as transfers and pledges, among its participants in such securities through electronic computerized book-entry changes in the accounts of its participants. This eliminates the need for physical movement of certificates.
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Participants in DTC include securities brokers and dealers, banks, trust companies and clearing corporations and may include certain other organizations. DTC is partially owned by some of these participants or their representatives.
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Access to DTC’s book-entry system is also available to others, such as banks, brokers, dealers and trust companies that clear through or maintain a custodial relationship with a participant, either directly or indirectly.
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The rules applicable to DTC and its participants are on file with the SEC.
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Clearstream, Luxembourg is a duly licensed bank incorporated as a société anonyme under the laws of Luxembourg and is subject to regulation by the Luxembourg Commission for the Supervision of the Financial Sector (Commission de Surveillance du Secteur Financier).
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Clearstream, Luxembourg holds securities for its customers and facilitates the clearance and settlement of securities transactions among them through electronic book-entry transfers between their accounts, thereby eliminating the need for physical movement of securities.
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Clearstream, Luxembourg provides other services to its customers, including safekeeping, administration, clearance and settlement of internationally traded securities and securities lending and borrowing.
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Clearstream, Luxembourg interfaces with domestic securities markets in over 30 countries through established depositary and custodial relationships.
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Clearstream, Luxembourg’s customers are worldwide financial institutions, including underwriters, securities brokers and dealers, banks, trust companies and clearing corporations. Clearstream’s US customers are limited to securities brokers and dealers and banks.
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Indirect access to Clearstream, Luxembourg is also available to other institutions such as banks, brokers, dealers and trust companies that clear through or maintain a custodial relationship with a Clearstream, Luxembourg customer.
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Euroclear is incorporated under the laws of Belgium as a bank and is subject to regulation by the Belgian Banking, Finance and Insurance Commission (Commission Bancaire et Financière) and the National Bank of Belgium (Banque Nationale de Belgique).
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Euroclear holds securities for its participants and facilitates the clearance and settlement of securities transactions among them. It does so through simultaneous electronic book-entry delivery against payment, thereby eliminating the need for physical movement of certificates and any risk from lack of simultaneous transfers of securities and cash.
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Euroclear provides various other services, including credit, custody, lending and borrowing of securities and tri-party collateral management. It interfaces with domestic markets in several countries.
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Euroclear participants include banks, including central banks, securities brokers and dealers and other professional financial intermediaries.
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Indirect access to Euroclear is also available to other firms that clear through or maintain a custodial relationship with a Euroclear participant, either directly or indirectly.
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All securities in Euroclear are held on a fungible basis. This means that specific certificates are not matched to specific securities clearance accounts.
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a right of conversion (exercisable then or later) into shares or other securities or to the acquisition of shares or other securities (including securities of the same description);
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a right to interest, the amount of which is or was determined to any extent by reference to the results of, or of any part of, a business or to the value of any property (save for interest which (i) reduces in the event of the results of a business or part of a business improving, or the value of any property increasing, or (ii) increases in the event of results of a business or part of a business deteriorating, or the value of any property diminishing);
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a right to interest the amount of which exceeds a reasonable commercial return on the nominal amount of the capital; or
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a right on repayment to an amount which exceeds the nominal amount of the capital and is not reasonably comparable with what is generally repayable (in respect of a similar nominal amount of capital) under the terms of issue of loan capital listed on the Official List of the London Stock Exchange.
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they are purchased by initial holders who purchase debt securities at the “issue price”, which will equal the first price to the public (not including bond houses, brokers or similar persons or organizations acting in the capacity of underwriters, placement agents or wholesalers) at which a substantial amount of the debt securities are sold for money;
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they are held as capital assets; and
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they are owned by United States Holders (as defined below).
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certain financial institutions;
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insurance companies;
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dealers in securities or foreign currencies;
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persons holding debt securities as part of a hedge;
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persons whose functional currency is not the US dollar;
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partnerships or other entities classified as partnerships for US federal income tax purposes;
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persons subject to the alternative minimum tax;
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persons subject to the Medicare contribution tax on net investment income;
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tax-exempt organizations;
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persons that own, or are deemed to own, 10% or more of the voting stock of AstraZeneca PLC; or
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persons carrying on a trade or business in the jurisdiction of the issuer through a permanent establishment.
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a citizen or resident of the United States;
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a corporation, or other entity taxable as a corporation for US federal income tax purposes, created or organized in or under the laws of the United States or of any political subdivision thereof; or
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an estate or trust the income of which is subject to US federal income taxation regardless of its source.
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through underwriters;
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through dealers;
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through agents; or
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directly to other purchasers.
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any underwriter, dealers or agents;
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their compensation;
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the net proceeds to us;
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the purchase price of the securities;
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the initial public offering price of the securities; and
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any exchange on which the securities will be listed.
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commercial and savings banks;
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insurance companies;
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pension funds;
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investment companies;
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educational and charitable institutions; and
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other similar institutions as we may approve.
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the validity of the arrangements; or
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the performance by us or the institutional investor.
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